As the familiar Johnny Test theme song plays, the scene opens up to the famous Test family. However, something seems different this time. Instead of the normal wacky experiments and adventures, the house is eerily quiet. Unexpectedly, a loud moan breaks the silence as the cam pans to the backyard. There, we see Mary and Susan, the twin sisters who are normally known for their intelligence and innocence, being damaged by a gigantic robot with tentacles.